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    • Clinicopathological analysis of mullerian adenosarcoma of the uterus

      Uterine mullerian adenosareoma is a very rate tumor clinically. Shi et al~1 has reported 9 uterine adenosarcomas among 116 uterine sarcomas during 11 years in West China Second Hospital.It consists of benign or atypical neoplastic glands within a sarcomatous stroma and represents only 8% of uterine sarcomas....

      2020-11-22 17:58:37瀏覽:9 mullerianadenosarcomauterinetumorclinicopathology

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    • Clinicopathological analysis of solitary fibrous tumor

      Objective: The aim of this study was to investigate the clinicopathologic characteristics, diagnosis and differential diagnosis, molecular genetics, treatment and prognosis of solitary fibrous tumor (SFT). Methods: The clinicopathological manifestations were analyzed retrospectively in 22 patients with surgically confirmed SFT. Results: There were 12 male patients and 10 female patients, with the age range 33–67 (mean 48.62) years. The SFTs originated from different from parts of the body, including 13 in the chest, 2 in the lungs, 3 in the abdomen, 1 in the lumbosacral area, 2 in the pelvis, and 1 in the left shoulder. There were 19 benign and 3 malignant tumors. Major clinical presentations were local masses and compression symptoms. Microscopy: the tumor was composed of areas of alternating hypercellularity and hypocellularity. The tumor cells were spindle to short-spindle shaped and arranged in fascicular or storiform pattern and hemangiopericytoma-like structure was presented. Immunohistochemically, Vimentin positive rate was 100% (22/22), Bcl-2 positive rate was 95.5% (21/22), CD99 positive rate was 86.4% (19/22), CD34 positive rate was 81.8 (18/22), focally positive for P53, as well as negative CK, S100 and Desmin. Ki67 labelling index was 2%–30%. Conclusion: SFT is a rare tumor which may be found in various parts of human body. SFT mostly is a benign tumor, but a few could be malignant. Its diagnosis mainly rely on its morphologic features and immunohistochemical profiles. The major treatment is to completely resect it by operation and long-term clinical follow-up is necessary....

      2020-11-22 17:58:37瀏覽:15 solitaryfibroustumor(SFT)clinicopathologydiagnosisdifferential

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    • Moving toward an understanding of the metastatic process in hepatocellular carcinoma

      INTRODUCTION
      Clinical factors contributing to the therapeutic challenge of hepatocellular carcinoma (HCC) are manifold :tumors arise often in patients with compromised liver function ,therefore limiting therapeutic options ;symptoms develop only at later stages of tumor progression ,and tumors tend to invade normal stuctures or occur in multiple locations simultaneously....

      2020-11-10 09:33:08瀏覽:14 carcinomaclonecellstumorculturedneoplasms

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    • Vadimezan的簡便合成

      2-氨基-3,4-二甲基苯甲酸經重氮化、溴代得到2-溴-3,4-二甲基苯甲酸,再與鄰羥基苯乙酸醚化和在多聚磷酸中發生分子內傅-克?;磻频胿adimezan,總收率為59%....

      2020-07-04 21:56:39瀏覽:1395 vadimezan腫瘤血管阻斷劑合成tumorvasculardisruptingagentsynthesis

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